HPV is a DNA virus that is an essential causative factor for cervical cancer. Persistent infection, particularly with high-risk HPV (HR-HPV) subtypes, plays a major role in the progression from precancerous cervical lesions to invasive cancer.
Real-time fluorescence PCR probing
Real-time PCR combines fluorescent probes with PCR primers, which allows accurate quantification of 13 high-risk subtypes in a sample. Viral load estimation of HPV is a particular advantage of real-time PCR.
Clinical Significances
New era of cervical cancer screening
Preferred alternative of ASCUS
HPV vaccines investigation
Follow-up on cervical lesions and prognosis treatment
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